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The 5 Steps to Managing Equine Cancer

Cancer is a devastating diagnosis for any pet owner, and horse owners are no exception. Horses, like humans and other animals, can develop cancer, which can manifest in various forms and affect different parts of their bodies. Understanding what to do if your horse is diagnosed with cancer can help you make informed decisions and provide the best possible care for your equine friend. This blog will guide you through the steps to take if your horse has cancer, your treatment options, management, and support.

Understanding Cancer in Horses

Cancer in horses can vary widely in terms of type, location, and severity. Common types of cancer in horses include:

Squamous Cell Carcinoma: SCC is a common type of cancer in horses and often affects the skin and mucous membranes. Squamous cell carcinoma (SCC) in horses is a serious and potentially life-threatening cancer that primarily affects the skin and mucous membranes. It often occurs in areas exposed to UV light, such as the eyes, genitalia, and non-pigmented skin, and can aggressively invade surrounding tissues, making early detection and treatment crucial. SCC is often linked to prolonged exposure to ultraviolet (UV) light, making horses with lighter skin or those living in sunny climates more susceptible.

Sarcoids: Tumor-like growths on the skin caused by bovine papillomavirus. Bovine papillomavirus (BPV) is a type of virus that infects cattle, leading to the development of warts or papillomas on the skin and mucous membranes. There are several types of BPV, each associated with different clinical presentations, ranging from benign warts to more serious conditions like cancer. BPV can also affect other species, including horses, where it is linked to the development of equine sarcoids. These are locally invasive skin tumors and can appear anywhere on the horse’s body. Sarcoids in horses are a common type of skin tumor, typically appearing as wart-like growths on the skin. Generally considered benign rather than cancerous. However, they can be locally aggressive, causing significant discomfort and potentially interfering with the horse’s daily activities and performance.

These benign tumors can vary in appearance and severity, often requiring treatment to prevent interference with the horse’s comfort and performance.

Melanoma: Melanoma in horses is a type of skin cancer most commonly seen in gray horses, especially as they age, where it is estimated that over 80% will develop some form of melanoma by the age of 15. This prevalence increases with age, making it a significant concern for aging gray horses.These tumors typically develop around the tail, anus, head, and neck, and while they can be benign, they have the potential to become malignant and spread to other parts of the body.

Lymphoma: Affects the lymphatic system and can manifest in various forms, including cutaneous and systemic lymphoma. Lymphoma in horses is a rare but serious type of cancer affecting the lymphatic system, which includes the lymph nodes, spleen, and other organs. Symptoms can vary widely depending on the affected organs, often including weight loss, lethargy, and swelling of the lymph nodes.

Each type of cancer requires specific diagnosis and treatment strategies, often involving a combination of surgical removal, chemotherapy, and radiation therapy. Early detection and veterinary intervention are crucial for managing these conditions effectively.

Step 1: Do Your Research If Your Horse Has Cancer

Researching your horse’s cancer can be an overwhelming yet crucial step in ensuring their health and well-being. 

Consult your veterinarian: Start by consulting with your veterinarian to understand the specific type of cancer your horse has been diagnosed with. 

Research on your own: Explore reputable veterinary websites, academic journals, and equine health forums to gather information on treatment options, prognosis, and advancements in equine oncology. 

Find a support group: Engaging with support groups and discussing with other horse owners who have faced similar challenges can provide valuable insights and emotional support. 

Staying informed: Staying informed empowers you to make the best decisions for your horse’s care and treatment plan.

Step 2: Explore Treatment Options for Equine Tumors

Treatment options for cancer in horses depend on the type and stage of cancer, as well as the overall health of the horse. Evaluating the benefits and drawbacks of each option can help horse owners make informed decisions. For the purpose of this blog we will focus on the pros and cons of surgery and radiation cancer therapy options for your horse and touch on chemotherapy, immunotherapy and cryotherapy as other options for equine cancer.

Surgery for Equine Tumors: Removal of the tumor or affected tissue is often the first line of treatment for accessible tumors.

Pros of Surgery for Equine Tumors

  • Surgery offers the chance to entirely remove localized tumors, potentially leading to a cure or significantly extending the horse’s life.
  • Removal of tumors can provide immediate relief from pain and discomfort associated with the mass.
  • Surgeons can precisely target the cancerous area, minimizing damage to surrounding healthy tissues.
  • When successful, surgery can reduce the likelihood of the cancer returning, especially if margins are clear of cancer cells.
  • Surgery allows for a more accurate diagnosis through biopsy, enabling better understanding of the cancer type and its progression.
  • The results from surgical biopsies can guide further treatment plans, including chemotherapy or radiation.

Cons of Surgery for Equine Tumors

  • As with any surgery, there is the potential of complications including infection, bleeding.
  • Adverse reactions to anesthesia poses risks especially for older or otherwise compromised horses.
  • Horses require significant recovery time, during which they may be vulnerable to complications or require extensive care.
  • There is a risk that not all cancerous cells will be removed, potentially leading to recurrence.
  • Surgery may not address micrometastases (small, undetected spread of cancer), necessitating additional treatments.
  • Surgical procedures for horses can be expensive, often requiring specialized facilities and experienced veterinary oncologists.
  • Access to equine surgical centers may be limited depending on geographic location, posing logistical challenges.
Surgery is an option for equine cancer, but is it the right option for your horse?

Radiation Therapy for Equine Tumors

When talking about radiation therapy your vet may mention external beam radiation, stereotactic radiation therapy or they may be aware of a more advanced targeted radiation therapy called Precision Radionuclide Therapy™ or PRnT™. Here are the pros and cons of each of the types of radiation therapy.

Precision Radionuclide Therapy™ – PRnT™ Radiation for Horses

Precision Radionuclide Therapy™ or PRnT™ is an advanced form of targeted radiation treatment that is safer and more effective while delivering up to 400gy of radiation to solid cancerous tumors. This method minimizes damage to surrounding healthy tissues by using precise needle injection to deliver the radiation directly into the tumor effectively killing the tumor from the inside out. Here’s a look at the pros and cons of targeted radiation, PRnT™ for horses with cancer.

Pros of Precision Radionuclide Therapy™ – PRnT™ Radiation for Equine Tumors

  • Performed as a single, outpatient treatment 
  • Delivers up to 400gy of Y-90 radioactive isotope to kill the tumor from the inside out.
  • Minimal damage, if any damage to surrounding healthy tissue.
  • Reduced risk of side effects like skin irritation and tissue damage.
  • Safer and minimally invasive as the radiation is contained inside the tumor using a patented Beta-Gel™ while killing the cancer from the inside out.
  • Provides significant pain relief by shrinking tumors quickly, thereby improving the horse’s overall quality of life.
  • If the IsoPet® Certified Veterinarian is a mobile vet, PRnT™ may be performed on site, reducing the trauma associated with travel to a clinic.

Cons of Precision Radionuclide Therapy™ Radiation for Equine Tumors

  • Cost of treatment depending on the size of the tumor.
  • Availability of this advanced technology is offered only at IsoPet® certified treatment centers which may require travel.
  • Anesthesia risks for older or otherwise compromised horses.
  • Horses might still experience localized minor side effects at the treatment site, such as temporary swelling or redness.

Precision Radionuclide Therapy™ – PRnT™ is an advanced form of patented targeted radiation therapy available in select universities and private clinics in the United States, offering a highly effective and precise treatment option for horses with solid cancerous tumors. PRnT™ is a safer and more effective option when treating solid equine tumors, however limited availability of treatment centers in the United States does require travel time and the cost may be a factor.

Stereotactic Radiation Therapy for Horses

Stereotactic radiation uses CT, MRI, or PET scans to pinpoint the exact location of the tumor and radiation is delivered by linear accelerators or high dose radiation beams directed at the tumor in multiple angles. These are the pros and cons of stereotactic radiation for horses.

Pros of Stereotactic Radiation for Equine Tumors

  • Effective in treating tumors in difficult-to-reach areas
  • Minimal damage to surrounding healthy tissue
  • Reduced risk of side effects like skin irritation and tissue damage.
  • Non-invasive and less physical trauma as a non-surgical treatment, it avoids the physical trauma associated with surgery, leading to quicker recovery times.
  • Provides significant pain relief by shrinking tumors that are causing discomfort or pain, thereby improving the horse’s overall quality of life.

Cons of Stereotactic Radiation for Equine Tumors

  • Requires multiple sessions 
  • Cost of treatment and precision equipment and specialized expertise required for targeted radiation therapy make it a costly option.
  • Only available at specialized veterinary oncology centers, which might require significant travel and logistics planning.
  • Requires multiple sessions
  • Multiple anesthesia risks as each treatment session may require anesthesia, posing risks especially for older or otherwise compromised horses.
  • Potential for recurrence necessitating ongoing monitoring and possibly additional treatments.
  • Horses might still experience localized side effects at the treatment site, such as temporary swelling, redness, or hair loss.

Stereotactic radiation therapy offers a highly effective and precise treatment option for horses with certain types of cancer. However, it is associated with high costs, limited availability, multiple treatments, and the risks associated with repeated anesthesia. Careful consideration and consultation with a veterinary oncologist are essential to determine if targeted radiation therapy is the best option for a horse’s specific cancer condition.

Stereotactic and EBRT require specialized equipment not readily available in most veterinary clinics.

External Radiation Therapy for Horses

External Beam Radiation Therapy (EBRT) is a treatment option for various cancers in horses. This technique involves directing high-energy radiation beams at the cancerous tissue from outside the body. Here are the pros and cons of EBRT. 

Pros of External Beam Radiation for Equine Tumors

  • EBRT does not require surgical incisions, reducing the risk of infection and complications associated with invasive procedures.
  • Horses can recover more quickly from EBRT compared to surgical options.
  • EBRT can be used to treat a range of tumors, including those that are not easily accessible surgically.
  • By shrinking tumors, EBRT can alleviate pain and improve the horse’s quality of life, particularly in cases of bone tumors.

Cons of External Beam Radiation for Equine Tumors

  • Cost of treatment and precision equipment and specialized expertise required for targeted radiation therapy make it a costly option.
  • EBRT requires specialized equipment and facilities,available at specialized veterinary oncology centers, which might require significant travel and logistics planning.
  • Multiple sessions are required over several weeks, requiring repeated visits to the treatment facility.
  • Transportation to the treatment center can be stressful for horses and owners.
  • Common side effects include skin reactions such as redness, irritation, and hair loss at the treatment site.
  • Radiation can impair the healing of tissues in the treated area, potentially leading to complications if the horse sustains an injury in the same location.
  • There is limited long-term data on the outcomes and potential late effects of EBRT in horses, making it harder to predict long-term prognosis.

EBRT may be a valuable tool in the treatment of cancer in horses, offering a non-invasive therapy with the potential for significant pain relief and preservation of function. However, it comes with challenges such as high costs, the need for specialized equipment, potential side effects, and the requirement for multiple treatment sessions. Horse owners and veterinarians should weigh these pros and cons when considering EBRT as a treatment option.

Melanoma in horses is a type of skin cancer most commonly seen in gray horses

Your veterinarian may also suggest these treatment options as a stand alone therapy or combined with surgery or radiation treatments. 

Chemotherapy: Uses drugs to kill cancer cells. This is less common in horses due to cost and potential side effects.

Immunotherapy: Boosts the horse’s immune system to fight cancer.

Cryotherapy: Freezing and destroying cancerous tissue, often used for skin tumors like sarcoids.

Your veterinarian will help you understand the benefits and risks of each treatment option and may refer you to a veterinary oncologist for specialized care.

Horse owners should work closely with their veterinarians to assess the best course of action based on the specific circumstances of their horse’s health and the type of cancer involved. This balanced perspective can help in making an informed decision that prioritizes the horse’s well-being and quality of life.

Creating a stress free environment for your horse is important.

Step 3: Develop a Management Plan

Managing a horse with cancer involves more than just medical treatment. It requires a comprehensive plan to ensure the horse’s quality of life. Consider the following aspects:

Nutrition

A balanced diet is crucial for a horse with cancer. Consult with a veterinary nutritionist to develop a diet that meets your horse’s nutritional needs and supports their immune system. Some general tips include:

– Providing high-quality forage and hay

– Supplementing with vitamins and minerals as needed

– Ensuring adequate hydration

– Avoiding high-sugar feeds that can compromise the immune system

Pain Management

Pain management is an essential part of cancer care. Your veterinarian may prescribe pain relief medications or recommend alternative therapies such as acupuncture or chiropractic care.

Environment

Create a comfortable and stress-free environment for your horse. Ensure they have a clean, dry, and safe living space. Minimize stress by maintaining a consistent routine and providing companionship if the horse is used to being around other horses.

Monitoring

Regular monitoring of your horse’s condition is vital. Keep a journal to track their symptoms, appetite, weight, and behavior. Regular veterinary check-ups are essential to assess the progression of the disease and adjust the treatment plan as needed.

Step 4: Emotional Support for You and Your Horse

Dealing with a cancer diagnosis can be emotionally challenging for both you and your horse. It’s important to take care of your mental and emotional well-being as well as your horse’s.

Support For Your Horse With Cancer

Companionship: Horses are social animals. Ensure they have companionship, whether it’s another horse or regular interaction with you.

Activities: Keep them engaged with light activities or grooming sessions to boost their morale.

Support For You As A Cancer Caregiver 

Support Network: Reach out to friends, family, or online communities for support and advice. Talking to others who have been through similar experiences can be comforting.

Professional Help: Consider seeking help from a counselor or therapist to manage the stress and emotions associated with caring for a sick horse.

Step 5: Considering Quality of Life and End-of-Life Decisions

As cancer progresses, there may come a time when you need to consider the quality of life of your horse. Discuss with your veterinarian the signs that indicate your horse’s quality of life is diminishing, such as:

– Persistent pain that cannot be managed

– Severe weight loss

– Inability to eat or drink

– Difficulty breathing or moving

Making end-of-life decisions is never easy, but sometimes euthanasia may be the kindest option to prevent suffering. Your veterinarian can guide you through this process and help you make an informed decision.

Conclusion

Facing a cancer diagnosis in your horse is a difficult and emotional journey, but with the right approach and support, you can ensure your horse receives the best care possible. Exploring treatment options, developing a comprehensive management plan, and seeking emotional support are crucial steps in this process. Our blog Supporting Your Horse’s Cancer Journey is full of information on helping your horse during these uncertain times. Remember, you are not alone—reach out to your veterinarian, support networks, and professionals to help you navigate this challenging time.

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Equine Cancer Sarcoids, Squamous Cell & Melanoma

Safe & Effective

IsoPet® delivers more than 90% of its therapeutic radiation within 10 days of a single treatment. Other therapies may require six weeks or more to deliver the full course.

Same Day Procedure

IsoPet® therapy is performed as an out-patient procedure and your pet may return home without subsequent concern for radiation exposure to your pet or family.

Minimal Side Effects

IsoPet® therapy is administered directly into the tumor without harm to the surrounding tissues or organs. Your pet will not feel any side effects of treatment.

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