Veterinarians

IsoPet® PRnT™ is a nonsurgical, same-day cancer treatment that is safe and effective.

Revolutionizing the Treatment of Pet Cancer with IsoPet®

“We have compelling evidence that IsoPet® will kill the primary tumors in a single treatment with a high therapeutic dose of Precision Radionuclide Therapy™-PRnT™”

– Dr. Michael Korenko, Sc.D. CEO of Vivos Inc.

Ordering IsoPet®

If you are an existing IsoPet® Certified Veterinarian please click the link below to enter tumor details on your patient and a member of our team will be in touch within the business day.

Common Types of Tumors IsoPet® Can Treat:

  • Equine Sarcoids*
  • Melanoma*
  • Soft Tissue Sarcoma (STS)*
  • Recurrent Soft Tissue Sarcoma*
  • Fibrosarcoma
  • Spindle Cell Sarcoma*
  • Perivascular Wall Tumors
  • Myopericytoma
  • Solitary Fibrous Tumor
  • Hemangiopericytoma*
  • Hemangiosarcoma
  • Squamous Cell Carcinoma (SCC)*
  • Ocular Squamous Cell Carcinoma*
  • Mast Cell Tumors (MCT)*
  • Multiple Perianal Tumors*
  • Periaal Adencarcinomas*
  • Synovial Myxoma*
  • Preputial Gland Adenocarcinoma* (ferret)
  • Epulis (Acanthomatous Ameloblastoma)
  • Anal Sac Adenocarcinoma*
  • Thyroid Carcinoma
  • IsoPet also treats Surgical Margins*

*Tumors IsoPet® has treated

How IsoPet® Works

Parallel Needle Injections
IsoPet® is continuously injected into the tumor in a grid pattern to ensure that the treatment is spread equally throughout the tumor — minimizing the dose to adjacent healthy tissues.

How to become a Certified IsoPet® Veterinarian

We at Vivos Inc. are at the forefront of veterinary oncology, dedicated to advancing cancer treatment through Isopet® Precision Radionuclide Therapy™. Our mission is to develop and deliver safer, more effective solutions for pets battling cancer, improving both their quality of life and treatment outcomes. Backed by scientific innovation, our team is committed to providing veterinarians with cutting-edge tools to revolutionize targeted radiation therapy. We believe in making a meaningful impact in the field of veterinary medicine, ensuring that animals receive the best possible cancer care through groundbreaking, precision-targeted treatments.

IsoPet® Treatment Kit

  • Vivos Peliter Chiller w/ Integrated Magnetic Stirrer
  • Shielded IsoPet® Vial Holders
  • Syringe shield
  • 1 cc BD Luer-lock Syringes
  • IsoPet® Instructions for Use
  • Vivos Peliter Chiller Instructions for Use
  • Training Aid for Use of Injection Guidance Form
  • IsoPet® Guidance Table

IsoPet® is a registered trademark of Vivos Inc.

A Safer Cancer Treatment for Small and Large Animals

Extending the lives of animals through our certified IsoPet® regional veterinarian clinics across the USA.

Safe & Effective

IsoPet® delivers more than 90% of its therapeutic radiation within 10 days of a single treatment. Other therapies may require six weeks or more to deliver the full course.

Same-Day Procedure

IsoPet® therapy is performed as an out-patient procedure and your pet may return home without subsequent concern for radiation exposure to your pet or family.

Minimal Side Effects

IsoPet® therapy is administered directly into the tumor without harm to the surrounding tissues or organs. Your pet should not feel any harmful side effects of treatment.

The Difference Between Targeted and External Beam Radiation

External Beam Radiation Therapy (EBRT)
External Beam Radiation delivers radiation from outside the body using high-energy beams, such as X-rays or protons, to target and destroy cancer cells. It involves directing radiation from an external machine towards the tumor. Despite advancements of image guided radiation, some side effects related to tissue damage may still occur.

Benefits of EBRT
– Can treat large areas.
– Can shrink a tumor before surgical removal.

Limitations of EBRT
– Difficulty targeting only the tumor without affecting surrounding tissues
– Requires multiple sessions.
– Challenging for equine cancer treatment due to the size and anatomy of horses.
– Side effects such as skin irritation, fatigue, and damage to nearby organs.

Targeted Radiation Therapy – IsoPet®’s PRnT™
IsoPet®’s patented Precision Radionuclide Therapy™ which provides a more precise treatment by injecting a radioactive isotope, Y-90, directly into the tumor without harm to surrounding tissues. This precision reduces the risk of side effects and damage to non-cancerous areas, enhancing overall treatment safety and effectiveness.

Benefits of Targeted Radiation such as PRnT™
-PRnT™ is an advanced treatment that delivers higher doses of radiation with pinpoint accuracy often in one session.
– PRnT™ places radioactive material (Y-90) directly inside or near the tumor, effectively killing the tumor from the inside out with minimal, if any, side effects.

Limitations of Targeted Radiation
-can be less effective for treating large, diffuse tumors or cancers that have metastasized tissues is critical.

These five factors demonstrate that targeted radionuclide radiation therapy is safer and more effective when compared to external beam radiation therapy.

1. Precision and Localization

  • Precision Radionuclide Therapy™ PRnT™: Uses the radioactive isotope Y-90 that specifically targets cancer cells, minimizing exposure to healthy tissue.
  • EBRT: Directs beams of radiation from outside the body, which can be challenging to avoid irradiating nearby healthy tissues completely.

2. Reduced Side Effects

  • Precision Radionuclide Therapy™ PRnT™: More localized radiation results in fewer side effects, which is crucial in sensitive areas.
  • EBRT:Can cause widespread side effects due to its impact on both the tumor and surrounding tissues.

3. Effectiveness for Specific Cancers

  • Precision Radionuclide Therapy™ PRnT™: Effective for cancers with specific markers or receptors.
  • EBRT: Used for a wider range of cancers but may be limited by the risk of damaging healthy tissue.

4. Potential for Combination Therapy

  • Precision Radionuclide Therapy™ PRnT™: Can be combined with other treatments, such as chemotherapy or surgery, to enhance effectiveness without significantly increasing toxicity.
  • EBRT: Also used in combination therapies, but the added radiation burden can limit the extent of additional treatments.

5. Radiation Dose Control

  • Precision Radionuclide Therapy™ PRnT™: Allows for controlled delivery of higher doses of radiation directly to the tumor, tailored to specific treatment needs.
  • EBRT: Dose modulation is possible but involves complex planning and advanced technology to ensure concentration on the tumor while sparing healthy tissue.

In conclusion, targeted radiation therapy has four main advantages over external beam radiation. Targeted radiation therapy is a major advancement in veterinary oncology, offering precise, millimeter-level tumor targeting that spares healthy tissue, reduces side effects, and often delivers higher doses in a single session to minimize stress for pets and owners. Especially for equine cancer, it provides a far more practical and effective alternative to external beam radiation, which is limited by the horse’s size and anatomy—resulting in safer, more efficient treatment and improved quality of life.

Interested in Offering
IsoPet® Treatment?

IsoPet® is a division of Vivos Inc. and interested veterinary clinics may inquire here and our team will reach out with the next steps to becoming one of our certified regional clinics offering our patented Precision Radionuclide Therapy™-PRnT™.

    From the IsoPet Knowledgebase

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